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Global Research Journal of Agricultural and Biological Sciences Vol. 3(4) pp.347–350 October 2012.
Available online http://www.globalresearchjournals.org/?a=journal&id=grjabs
Copyright ©2012 Global Research Journals
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Synergism between ethanol leaf extract of Canarium schwenfurthii and antimicrobial drugs on some pathogenic microbes
ODUNBAKU, O. A. AND GANIYU, S. K.
Plant Science and Applied Zoology,Olabisi Onabanjo University,
P. M.B. 2002. Ago-lwoye, Ogun State.
Correspondence:esthershow2005@yahoo.com
Abstract
The antimicrobial activity of ethanol leaf extract of Canarium schwenfurthii was tested against five bacteria (Staphyloccocus aureus, Staphylococcus albus, Klebseilla pneumonia, Pseudomonas aeruginosa and Proteus mirabilis) and six fungi (Rhizopus sp, Penicillin oxalicum, Aspergillus tamari, Aspergillus niger, Fusarium oxysporum and Fusarum vacilitus). The result revealed that the plant had inhibitory activity against all the tested microbes. The protein synthesis inhibitors were more active against the organisms than the cell wall and nucleic acid inhibitors. The antifungal drugs produced varied inhibitory reactions against the fungi tested. The synergetic effect of plant extract and antimicrobial drugs produced greater inhibitory effect than the plant extract or drugs alone. The phytochemical screening of the plant showed the presence of Alkaloid, Cardenolide, Saponin, and Tannin while Anthraquinone was absent.
Keywords: Canarium schwenfurthii, synergism antimicrobial, pathogenic microbes.